Cation Interactions and Membrane Potential Induce Conformational Changes in NaPi-IIb
نویسندگان
چکیده
منابع مشابه
pivotal residue for cation-induced conformational changes
The cation binding characteristics of the mutant E327A formed in the sheep al isoform of the Na+,K+-ATPase were examined using [3H]ouabain binding as a function of monovalent cation concentrations. Equilibrium competition binding assays in the presence of Mg2+, inorganic phosphate and various amounts of unlabelled ouabain indicated that both wild-type sheep al protein and the E327A mutant expre...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2016
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2016.07.025